Article
The First Report of Macrolide-Resistant Bordetella pertussis Isolation in Japan.
Japanese journal of infectious diseases - 24 Sept 2020
Yamaguchi Takahiro, Kawasaki Yasuhiro, Katsukawa Chihiro, Kawahara Ryuji, Kawatsu Kentaro
Abstract excerpt
We report the first detection of a macrolide-resistant Bordetella pertussis strain in Japan. The isolate was highly resistant to the macrolides (minimum inhibitory concentrations for erythromycin and clarithromycin: > 256 µg/ml, for azithromycin: 32 µg/ml) and A2047G mutation was identified in the 23S rRNA. The Multilocus Sequence Typing and Multilocus Variable Number of Tandem Repeat Analysis genotypes of this...
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