Article
Redefining Treatment Paradigms for Glioma in Adolescents and Young Adults: Population-Based Evidence for Molecular Classification.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2026
Qu Shanqiang, Pan Qiuming, Zhang Xin, Wang Junxi, Li Hongrui, Huang Yudi, Liao Kuilin, Ye Zhi, Ainiwan Yilamujiang, Yi Guozhong, Li Zhiyong, Liu Junlu, Hou Xiaomin, Xu Haiyan, Chen Zhuoyang, Mei Fen, Liu Tao, Zhang Xi'an, Qi Songtao, Huang Guanglong
Abstract excerpt
PURPOSE: Gliomas represent the second most common malignancy and leading cause of cancer death in adolescents and young adults (AYA; ages 15-39 years), yet their molecular landscape remains incompletely characterized. This study aims to characterize the molecular landscape of primary gliomas in AYAs by integrating multi-omics data. EXPERIMENTAL DESIGN: We recruited a cohort of patients with histopathologically...
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