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Drug-gene interactions and the risk of diabetic microvascular complications: A population-based cohort study.

Diabetes, obesity & metabolism - 1 Apr 2026

Li Ning, Sun Jiao, Li Haibin, Li Changwei, Wang Xiao, Ji Jianguang, Ren Tianmin, Wen Yalu, Zheng Deqiang

Abstract excerpt

AIMS: Drug-gene interactions (DGIs) modify drug response and safety, yet their influence on diabetic microvascular complications remains unclear. This study aimed to elucidate the role of DGIs in these complications. MATERIALS AND METHODS: Using UK Biobank (UKB) data, we identified medications frequently prescribed to individuals with diabetes and defined DGIs based on the Food and Drug Administration (FDA) and...

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PMID: 41582657
DOI: 10.1111/dom.70501

Genes

CYP2C19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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