Article

Identification and genetic validation of drug-comorbidity interactions in type 2 diabetes using data-driven disease trajectory analysis

2019-10-22

Abstract excerpt

Given various risk profiles, manifestations, comorbidities, and outcomes for individuals with Type 2 diabetes mellitus (T2D), a one-size-fits-all approach towards treatment and management is inadequate, and there is a clear need for personalized medications to reduce rates of complications and comorbidities. Here, we leveraged comprehensive Electronic Medical Records (EMR) to identify associations between T2D como...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5a12143-d355-5e44-b847-77eb5679c3aa
DOI: 10.1101/814392

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification and genetic validation of drug-comorbidity interactions in type 2 diabetes using data-driven disease trajectory analysisDOI 10.1101/814392Read

Current progress in pharmacogenomics of Type 2 diabetes: A systemic overview.Semantic proximity Read

Updates In Common Genetic Variants May Help Guide Drug Selection For Treating Uncontrolled DiabetesSemantic proximity Read

Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicineSemantic proximity Read

Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical PracticeSemantic proximity Read

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbiditiesSemantic proximity Read

Insights into the molecular underpinning of type 2 diabetes complicationsSemantic proximity Read

Current Progress in Pharmacogenetics of Second-Line Antidiabetic Medications: Towards Precision Medicine for Type 2 DiabetesSemantic proximity Read

Pharmacogenetic studies update in type 2 diabetes mellitusSemantic proximity Read

Discovery of 318 novel loci for type-2 diabetes and related micro- and macrovascular outcomes among 1.4 million participants in a multi-ethnic meta-analysisSemantic proximity Read

Effect of metabolic genetic variants on long-term disease comorbidity in patients with type 2 diabetes.Semantic proximity Read

Genetic associated complications of type 2 diabetes mellitus.Semantic proximity Read

Precision Medicine in Patients with Differential Diabetic Phenotypes: Novel Opportunities from Network Medicine.Semantic proximity Read