Article
Drug-gene interactions in older patients with coronary artery disease.
BMC geriatrics - 26 Oct 2024
Zhang Shizhao, Lv Chao, Dong Lisha, Wu Yangxun, Yin Tong
Abstract excerpt
BACKGROUND: Older patients with coronary artery disease (CAD) are particularly vulnerable to the efficacy and adverse drug reactions, and may therefore particularly benefit from personalized medication. Drug-gene interactions (DGIs) occur when an individual's genotype affects the pharmacokinetics and/or pharmacodynamics of a victim drug. OBJECTIVES: This study aimed to investigate the impact of...
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