Article
Sputum from Individuals with Primary Ciliary Dyskinesia Drives M2-like Macrophage Polarization.
Lung - 26 Jan 2026
Wåhlander Jenny, Schmidt Tobias, Hansen Christine R, Kahn Robin, Påhlman Lisa I
Abstract excerpt
INTRODUCTION: Primary ciliary dyskinesia (PCD) is a rare, congenital condition in which impaired ciliary function leads to bronchiectasis and progressive lung function decline. Bronchiectasis development is believed to involve infection and inflammation but is incompletely understood. Macrophages play a central role in cellular immune response, contributing to both pathogen clearance and immunoregulation....
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