Article
Macrophage dysfunction in the pathogenesis and treatment of asthma.
The European respiratory journal - 1 Sept 2017
Fricker Michael, Gibson Peter G
Abstract excerpt
Asthma is a chronic respiratory condition frequently associated with aberrant airway and systemic inflammation. Various inflammatory phenotypes in asthmatic airways have been described that relate to clinical phenotypes and impact on responses to conventional and novel asthma therapies. Macrophages are abundant immunocytes in the lung, capable of mounting diverse responses required for homeostasis and defence...
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