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Article

Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection.

BMC genomics - 22 Jan 2026

Falchi Laura, Cesarani Alberto, Brito Luiz F, Mastrangelo Salvatore, Pauciullo Alfredo, Macciotta Nicolò P P, Gaspa Giustino

Abstract excerpt

BACKGROUND: Runs of homozygosity (ROH) occurrence in animal genomes may result from a high level of relatedness within the population or from positive selection. ROH investigation enables the assessment of the degree of individual autozygosity at the genome-wide level, providing insights into genetic background and development history of a population. In this context, the main objectives of this study were to: 1)...

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Identifiers

PMID: 41572150
DOI: 10.1186/s12864-026-12564-7
PMCID: PMC12908255

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