Article
Genome-wide identification of runs of homozygosity islands and associated genes in local dairy cattle breeds.
Animal : an international journal of animal bioscience - 1 Dec 2018
Mastrangelo S, Sardina M T, Tolone M, Di Gerlando R, Sutera A M, Fontanesi L, Portolano B
Abstract excerpt
Runs of homozygosity (ROH) are widely used as predictors of whole-genome inbreeding levels in cattle. They identify regions that have an unfavorable effect on a phenotype when homozygous, but also identify the genes associated with traits of economic interest present in these regions. Here, the distribution of ROH islands and enriched genes within these regions in four dairy cattle breeds were investigated....
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