Article
Genomic inbreeding estimation in small populations: evaluation of runs of homozygosity in three local dairy cattle breeds.
Animal : an international journal of animal bioscience - 1 May 2016
Mastrangelo S, Tolone M, Di Gerlando R, Fontanesi L, Sardina M T, Portolano B
Abstract excerpt
In the local breeds with small population size, one of the most important problems is the increase of inbreeding coefficient (F). High levels of inbreeding lead to reduced genetic diversity and inbreeding depression. The availability of high-density single nucleotide polymorphism (SNP) arrays has facilitated the quantification of F by genomic markers in farm animals. Runs of homozygosity (ROH) are contiguous...
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