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Article

Runs of homozygosity reveal genome-wide autozygosity in Italian sheep breeds.

Animal genetics - 1 Feb 2018

Mastrangelo S, Ciani E, Sardina M T, Sottile G, Pilla F, Portolano B

Abstract excerpt

The availability of dense single nucleotide polymorphism (SNP) assays allows for the determination of autozygous segments based on runs of consecutive homozygous genotypes (ROH). The aim of the present study was to investigate the occurrence and distribution of ROH in 21 Italian sheep breeds using medium-density SNP genotypes in order to characterize autozygosity and identify genomic regions that frequently...

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PMID: 29333609
DOI: 10.1111/age.12634

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