Article
Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants.
Nature genetics - 1 Feb 2026
Geller Frank, Wu Xiaoping, Lammi Vilma, Abner Erik, Valliere Jesse Tyler, Nastou Katerina, Burns Angus, Rasmussen Morten, Andersson Niklas Worm, Quinn Liam, Aagaard Bitten, Banasik Karina, Bliddal Sofie, Boding Lasse, Brunak Søren, Brøns Nanna, Bybjerg-Grauholm Jonas, Christoffersen Lea Arregui Nordahl, Didriksen Maria, Dinh Khoa Manh, Erikstrup Christian, Feldt-Rasmussen Ulla, Grønbæk Kirsten, Kaspersen Kathrine Agergård, Mikkelsen Christina, Nielsen Claus Henrik, Nielsen Henriette Svarre, Nielsen Susanne Dam, Nissen Janna, Sequeros Celia Burgos, Tommerup Niels, Ullum Henrik, Spiliopoulos Lampros, Bager Peter, Hviid Anders, Sørensen Erik, Pedersen Ole Birger, Lane Jacqueline M, Lassaunière Ria, Ollila Hanna M, Ostrowski Sisse Rye, Feenstra Bjarke
Abstract excerpt
The host genetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have previously been studied based on cases from the earlier waves of the pandemic in 2020 and 2021, identifying 51 genomic loci associated with infection and/or severity. SARS-CoV-2 has shown rapid sequence evolution, increasing transmissibility, particularly for Omicron variants, which raises the question of whether this affected...
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