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Article

Risk-reducing decisions regarding germline BRCA pathogenic variant: focusing on the timing of genetic testing and RRSO.

Journal of medical genetics - 21 Mar 2024

Abe Akiko, Nomura Hidetaka, Fusegi Atsushi, Yunokawa Mayu, Ueki Arisa, Habano Eri, Arakawa Hiromi, Kaneko Keika, Minoura Yuko, Inari Hitoshi, Ueno Takayuki, Kanao Hiroyuki

Abstract excerpt

BACKGROUND: In Japan, the public insurance policy was revised in 2020 to cover hereditary breast and ovarian cancer (HBOC), including genetic testing and surveillance, for patients with breast cancer (BC). Consequently, the demand for risk-reducing salpingo-oophorectomy (RRSO) has increased. This study aimed to clarify the changes in the demand and timing of genetic testing and RRSO associated with public...

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Identifiers

PMID: 38124001
DOI: 10.1136/jmg-2023-109549
PMCID: PMC10982634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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