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Management of ovarian and breast cancer risk in non-BRCA HBOC pathogenic variant carriers in a large California health care system.

Gynecologic oncology - 1 Dec 2022

Powell C Bethan, Laurent Cecile, Garcia Christine, Hoodfar Elizabeth, Karlea Audrey, Kobelka Christine, Lee Jaimie, Roh Janise, Kushi Lawrence H

Abstract excerpt

PURPOSE: To describe breast and ovarian cancer risk reduction strategies in the clinical management of women who test positive for non-BRCA hereditary breast and ovarian cancer (HBOC) pathogenic variants compared to those who test positive for pathogenic BRCA variants or have negative germline panel testing. METHODS: Examination of imaging and preventive surgeries in women undergoing HBOC genetic testing from...

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PMID: 36220669
DOI: 10.1016/j.ygyno.2022.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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