Article
Tumor copy number instability is a significant predictor for late recurrence after radical surgery of pancreatic ductal adenocarcinoma.
Cancer medicine - 1 Oct 2020
Wen Chenlei, Deng XiaXing, Ren Dandan, Song Xue, Chen Hao, Wang Jiancheng, Jin Jiabin, Cheng Dongfeng, Xu Zhiwei, Zhang Jun, Xie Junjie, Qi Wenjing, Gu Jiangning, Peng Chenghong, Chen Dan, Chen Shi, Shen Baiyong, Zhan Qian
Abstract excerpt
OBJECTIVE: Our study examined the association between molecular features and clinical results of pancreatic ductal adenocarcinoma (PDAC) patients, aiming to explore the genomic determinants of the recurrence and prognosis of PDAC after surgical removal. METHODS: This retrospective study analyzed 181 PDAC patients who received pancreatectomy and adjuvant chemotherapy, with 67 patients in the training set. An...
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