Article
Targeted amplicon sequencing for primary tumors and matched lymph node metastases in patients with extrahepatic cholangiocarcinoma.
HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Jul 2022
Yamada Toru, Nakanishi Yoshitsugu, Hayashi Hideyuki, Tanishima Shigeki, Mori Ryo, Fujii Kyoko, Okamura Keisuke, Tsuchikawa Takahiro, Nakamura Toru, Noji Takehiro, Asano Toshimichi, Matsui Aya, Tanaka Kimitaka, Watanabe Yusuke, Kurashima Yo, Ebihara Yuma, Murakami Soichi, Shichinohe Toshiaki, Mitsuhashi Tomoko, Hirano Satoshi
Abstract excerpt
BACKGROUND: Lymph node metastasis (LNM) is one of the most adverse prognostic factors in extrahepatic cholangiocarcinoma (EHCC) cases. As next-generation sequencing technology has become more widely available, the genomic profile of biliary tract carcinoma has been clarified. However, whether LNMs have additional genomic alterations in patients with EHCC has not been investigated. Here, we aimed to compare the...
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