Synergistic impact of insulin resistance and hepatic fibrosis on cardiovascular events in patients with coronary artery disease: A machine learning subtyping and interaction analysis.

Abstract excerpt

BACKGROUND AND AIMS: Insulin resistance (IR) and hepatic fibrosis are significant yet underexplored synergistic risk factors for cardiovascular events in coronary artery disease (CAD). We investigated the interaction between the triglyceride-glucose (TyG) index and liver fibrosis scores (FIB-4, BARD) for risk prediction. METHODS AND RESULTS: Within a prospective cohort of 14,660 CAD patients, we performed a...

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