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Article

Childhood adversity and 5-HTTLPR across mental health outcomes: A transdiagnostic meta-analysis.

Child abuse & neglect - 1 Mar 2026

Shivam Vishnu

Abstract excerpt

BACKGROUND: Childhood maltreatment is associated with increased risk for various psychiatric disorders, although individual responses to early adversity vary. The serotonin transporter-linked polymorphic region (5-HTTLPR) has been examined as a potential moderator of sensitivity to environmental stress, but findings across studies have been inconsistent. OBJECTIVE: This meta-analysis examined whether 5-HTTLPR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41546921
DOI: 10.1016/j.chiabu.2026.107901

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