Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders.

doi:10.1038/sj.npp.1301422

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Article

Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2008

Stein Murray B, Schork Nicholas J, Gelernter Joel

Abstract excerpt

Anxiety sensitivity (AS) is a dispositional characteristic that predisposes to the development of anxiety disorders (eg, panic and post-traumatic stress disorder) and major depression. AS is subject to genetic and environmental influences, the former as yet unidentified and the latter known to in...

Topics

Adult
Anxiety
Child
Child Abuse
Environment
Ethnicity
Female
Genotype
Humans
Male
Regression Analysis
Serotonin Plasma Membrane Transport Proteins
Surveys and Questionnaires

Source

Open in PubMed

Identifiers

PMID: 17460615
DOI: 10.1038/sj.npp.1301422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-17460615-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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