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Article

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children.

Biological psychiatry - 15 Apr 2006

Kaufman Joan, Yang Bao-Zhu, Douglas-Palumberi Heather, Grasso Damion, Lipschitz Deborah, Houshyar Shadi, Krystal John H, Gelernter Joel

Abstract excerpt

BACKGROUND: Child abuse and genotype interact to contribute to risk for depression in children. This study examined gene-by-gene and gene-by-environment interactions. METHODS: The study included 196 children: 109 maltreated and 87 nonmaltreated comparison subjects. Measures of psychiatric symptomatology and social supports were obtained using standard research instruments, and serotonin transporter (5-HTTLPR)...

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Source

Identifiers

PMID: 16458264
DOI: 10.1016/j.biopsych.2005.10.026

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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