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Article

Genetically predicted high-density lipoprotein traits and pan-disease risk: a systematic review.

Epidemiologic reviews - 29 Jan 2026

Wu Jiexi, Su Bohan, Fan Zhiyao, Zhan Hanxiang

Abstract excerpt

High-density lipoprotein (HDL) is a highly heterogeneous lipoprotein with multiple physiological functions. However, observational studies present conflicting evidence regarding its association with various diseases. This review systematically summarizes evidence from Mendelian randomization (MR) studies to investigate the causal relationships between HDL-related biomarkers and a wide spectrum of disease...

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PMID: 41536214
DOI: 10.1093/epirev/mxag001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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