Article
Unlocking CRISPR-Cas9 editing for widely diverse Dictyostelid species.
Molecular systems biology - 1 Apr 2026
Garriga-Canut Mireia, Cannon Nikki, Benton Matt, Zanon Andrea, Horsfield Samuel T, Scheurich Jacob, Remans Kim, Lees John, Paix Alexandre, van Gestel Jordi
Abstract excerpt
Dictyostelids are a species-rich clade of cellular slime molds that are widely found in soils and have been studied for over a century. Due to a lack of genome editing methods, most molecular research in Dictyostelids has focused on only a single species, Dictyostelium discoideum, which has severely limited broad-scale comparative analyses. Here, we introduce the first CRISPR-Cas9 editing approach that is...
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