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Article

Causal cues and mediating pathways of potential genetic mechanisms of subarachnoid hemorrhage and intracerebral hemorrhage.

Medicine - 9 Jan 2026

Wang Yang, Yang Huimin, Liu Yanying, Fan Furong, Wu Jing, Hou Yaqi, Gong Wanli, He Peifeng, Yu Qi

Abstract excerpt

Subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) are the primary subtypes of hemorrhagic stroke. Obesity and dietary factors may play significant roles in their pathogenesis, yet the genetic causal relationships and potential mediating pathways remain unclear. This study utilized publicly available genome-wide association study databases and applied Mendelian randomization (MR) methods to...

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Identifiers

PMID: 41517756
DOI: 10.1097/MD.0000000000047111
PMCID: PMC12795027

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