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Causal cues and mediating pathways of potential genetic mechanisms of subarachnoid hemorrhage and intracerebral hemorrhage.

Medicine - 9 Jan 2026

Wang Yang, Yang Huimin, Liu Yanying, Fan Furong, Wu Jing, Hou Yaqi, Gong Wanli, He Peifeng, Yu Qi

Abstract excerpt

Subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) are the primary subtypes of hemorrhagic stroke. Obesity and dietary factors may play significant roles in their pathogenesis, yet the genetic causal relationships and potential mediating pathways remain unclear. This study utilized publicly available genome-wide association study databases and applied Mendelian randomization (MR) methods to...

Topics

Subarachnoid Hemorrhage
Humans
Cerebral Hemorrhage
Genome-Wide Association Study
Obesity
Alcohol Drinking
Risk Factors
Mendelian Randomization Analysis
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41517756
DOI: 10.1097/MD.0000000000047111
PMCID: PMC12795027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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