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Article

Influence of APOE4 Genotypes on Nutrient-Cognition Relationship in Taiwanese Older Adults: Longitudinal Findings from the HALST.

Nutrients - 28 Dec 2025

Lai Rai-Hua, Yang Shiu-Ju, Hsu Pei-Yi, Chen Yi-Chung, Chuang Shu-Chun, Hsu Chih-Cheng, Hsiung Chao Agnes, Kuo Fang-Lin

Abstract excerpt

Background: Older adults carrying the APOE4 allele are at elevated risk for cognitive decline. To clarify how dietary patterns may influence cognitive deterioration in this high-risk group, further investigation is needed. Methods: This prospective cohort study followed 1420 Taiwanese adults aged 65 years or older. Dietary intake was assessed using a validated food frequency questionnaire, and cognitive function...

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Identifiers

PMID: 41515222
DOI: 10.3390/nu18010106
PMCID: PMC12788161

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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