Article
Healthy lifestyle factors outweigh influence of APOE genetic risk on extending cognitively healthy life expectancy among Chinese older adults: evidence from a nationwide cohort study.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Apr 2025
Ren Longbing, Hu Fan, Walsh Sebastian, Jin Xurui, Hu Yang, Li Shaojie, Jiang Yuling, Yu Mingzhi, Wu Yifei, Zang Grace Yuange, Liu Keyang, Chen Huashuai, Sun Jing, Zhang Yan, Shirai Kokoro, Zeng Yi, Samus Quincy M, Livingston Gill, Yao Yao
Abstract excerpt
INTRODUCTION: Understanding the interplay between genetic factors and lifestyle choices in cognitive health is crucial for enhancing late-life quality. This study examines the effects of Apolipoprotein E (APOE) genotypes and healthy lifestyles on life expectancy with and without cognitive impairment (CI) in Chinese older adults. METHODS: Data from 6488 participants aged at least 65 in the Chinese Longitudinal...
Topics
- Humans
- Male
- Female
- Life Expectancy
- Aged
- China
- Healthy Lifestyle
- Cognitive Dysfunction
- Cohort Studies