Article
Spatial Phenotype of the Mast Cell Population in Endometritis of Various Severities.
Cells - 24 Dec 2025
Mikhalev Sergey, Kostin Andrey, Kurtser Mark, Radzinsky Victor, Orazov Mekan, Alekhnovich Alexander, Prikhodko Aleksandra, Demyashkin Grigory, Klabukov Ilya, Baranovskii Denis, Elieh-Ali-Komi Daniel, Buchwalow Igor, Tiemann Markus, Mikhaleva Liudmila, Atiakshin Dmitrii
Abstract excerpt
Endometritis features an inflammatory milieu in the endometrium, accompanied by the recruitment of immunocompetent cells, including mast cells (MCs). The mechanisms underlying MC involvement in chronic endometritis (CE) and fibrous niche formation remain poorly understood, particularly regarding spatial intercellular interactions in situ. In this study, we used multiplex immunohistochemistry and quantitative...
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