Article

Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune response

2023-10-16

Abstract excerpt

Endometriosis (EM), characterized by the presence of endometrial-like tissue outside the uterus, is the leading cause of chronic pelvic pain and infertility in females of reproductive age. Despite its high prevalence, the molecular mechanisms underlying EM pathogenesis remain poorly understood. The endocannabinoid system (ECS) is known to influence several cardinal features of this complex disease including pain,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 00faf1d7-90e2-5062-989a-2374b94451b3
DOI: 10.1101/2023.10.11.561929

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune responseDOI 10.1101/2023.10.11.561929Read

Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune responseSemantic proximity Read

Endometriosis as a Systemic and Complex Disease: Toward Phenotype-Based Classification and Personalized Therapy.Semantic proximity Read

Understanding Endometriosis: A Broad Review of Its Causes, Management, and ImpactSemantic proximity Read

A cellular and molecular portrait of endometriosis subtypesSemantic proximity Read

Identification and Exploration of Novel Macrophage M2-Related Biomarkers and Potential Therapeutic Agents in EndometriosisSemantic proximity Read

High-Resolution Spatial Transcriptomics Reveals Fibroblast and Neuroimmune Microenvironments in Endometriosis LesionsSemantic proximity Read

The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosisSemantic proximity Read

Molecular mechanisms contributing to the pathogenesis of endometriosis.Semantic proximity Read

The genetics and biochemistry of endometriosisSemantic proximity Read

Distinct subtypes of endometriosis identified based on stromal-immune microenvironment and gene expression: implications for hormone therapySemantic proximity Read

Unraveling immunotherapeutic targets for endometriosis: a transcriptomic and single-cell analysisSemantic proximity Read

Single cell analysis of endometriosis reveals a coordinated transcriptional program driving immunotolerance and angiogenesis across eutopic and ectopic tissuesSemantic proximity Read