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Article

From genotype to phenotype in early childhood asthma.

The Journal of allergy and clinical immunology - 1 Apr 2026

Jensen Signe Kjeldgaard, Fischer-Rasmussen Kasper, Eliasen Anders, Hesselberg Laura Marie, Brustad Nicklas, Melgaard Mathias Elsner, Werge Thomas, Bybjerg-Grauholm Jonas, Nyegaard Mette, Merid Simon Kebede, Melen Erik, George Elizabeth, Duan Qingling, Subbarao Padmaja, Schoos Ann-Marie Malby, Stokholm Jakob, Chawes Bo, Pedersen Casper Emil Tingskov, Bønnelykke Klaus

Abstract excerpt

BACKGROUND: Asthma and recurrent wheeze in the first years of life represent a heterogeneous and poorly understood syndrome with a need to understand to what extent phenotypes reflect distinct underlying mechanisms. OBJECTIVE: We sought to investigate whether specific genetic asthma mechanisms, represented by genetic risk loci, were associated with specific disease courses and asthma phenotypes. METHODS: Known...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41500470
DOI: 10.1016/j.jaci.2025.12.1006

Genes

CDHR3
GSDMB
ABO
FUT2
IL13
IL1RL1
IL33
TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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