Comparative analysis of IHC, AMRS-PCR, and ddPCR for BRAF V600E mutation detection in papillary thyroid carcinoma.

doi:10.1016/j.ctarc.2025.101085

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Comparative analysis of IHC, AMRS-PCR, and ddPCR for BRAF V600E mutation detection in papillary thyroid carcinoma.

Cancer treatment and research communications - 1 Jan 2026

Chang Chen, Fang Guodong, Lei Jianyuan, Liu Lele, Wang Guorong, Li Wensheng

Abstract excerpt

BACKGROUND: The BRAF V600E mutation is the most frequent driver alteration in papillary thyroid carcinoma (PTC) and plays an important role in diagnosis, risk stratification, and treatment planning. Commonly used detection methods include immunohistochemistry (IHC), amplification-refractory mutat...

Topics

Humans
Proto-Oncogene Proteins B-raf
Thyroid Cancer, Papillary
Polymerase Chain Reaction
Retrospective Studies
Thyroid Neoplasms
Female
Immunohistochemistry
Mutation
Middle Aged
Male
Adult
Sensitivity and Specificity
Aged

Source

Open in PubMed

Identifiers

PMID: 41496267
DOI: 10.1016/j.ctarc.2025.101085

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-41496267-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics