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Article

Utility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules.

BMC cancer - 26 Oct 2021

Rosvall Brandon R, Kostiuk Morris, Williams Jordana, Matkin Ashlee, Harris Jeffrey, Seikaly Hadi, O'Connell Daniel A, Biron Vincent L

Abstract excerpt

BACKGROUND: Mutations involving BRAF and TERT are important predictors of disease severity in thyroid cancer, but molecular testing is limited by cost and lack of adequate tissue sample. This study aimed to assess the utility of BRAFV600E and TERT testing using droplet digital PCR (ddPCR) as a diagnostic and prognostic tool for thyroid fine needle aspirate biopsy (FNAB). METHODS: Patients with thyroid nodules...

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Identifiers

PMID: 34702207
DOI: 10.1186/s12885-021-08810-8
PMCID: PMC8547072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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