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Article

Utility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules.

BMC cancer - 26 Oct 2021

Rosvall Brandon R, Kostiuk Morris, Williams Jordana, Matkin Ashlee, Harris Jeffrey, Seikaly Hadi, O'Connell Daniel A, Biron Vincent L

Abstract excerpt

BACKGROUND: Mutations involving BRAF and TERT are important predictors of disease severity in thyroid cancer, but molecular testing is limited by cost and lack of adequate tissue sample. This study aimed to assess the utility of BRAFV600E and TERT testing using droplet digital PCR (ddPCR) as a di...

Topics

Female
Humans
Male
Middle Aged
Mutation
Polymerase Chain Reaction
Proto-Oncogene Proteins B-raf
Telomerase
Thyroid Nodule

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34702207
DOI: 10.1186/s12885-021-08810-8
PMCID: PMC8547072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34702207-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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