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Article

Causal effects of inflammatory bowel disease on brain structure: A Mendelian randomization study.

Medicine - 2 Jan 2026

He Ying, He Jian, Chen Chunlan

Abstract excerpt

Brain structural abnormalities are common in patients with Crohn disease (CD) and ulcerative colitis (UC). However, the precise causal relationships between them remain uncertain. Hence, this study aimed to assess the causal effects of CD and UC on brain structure by using Mendelian randomization (MR) analysis. Single nucleotide polymorphisms retrieved from genome-wide association studies are usually selected as...

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Identifiers

PMID: 41496026
DOI: 10.1097/MD.0000000000046867
PMCID: PMC12778087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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