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Article

Increased responsivity to pharmacological manipulations of dopamine D1 receptors in binge eating prone rats.

Physiology & behavior - 15 Mar 2026

Johnson Alexander W, Klump Kelly L, Culbert Kristen M, Lee-Tanner Jenna, Sisk Cheryl L

Abstract excerpt

Binge eating is a key feeding behavior that is a core symptom of most major eating disorders, with disruptions in the neurotransmitter dopamine gaining significant interest as a potential risk factor. In the current study we sought to examine functional and molecular changes that may underlie alterations in the dopamine system in female rats prone to binge eating. Rats received six feeding tests with intermittent...

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Identifiers

PMID: 41478312
DOI: 10.1016/j.physbeh.2025.115216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

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