Article
Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes.
Progress in neuro-psychopharmacology & biological psychiatry - 7 Aug 2012
Davis Caroline, Levitan Robert D, Yilmaz Zeynep, Kaplan Allan S, Carter Jacqueline C, Kennedy James L
Abstract excerpt
OBJECTIVE: While the study of binge eating disorder (BED) has burgeoned in the past decade, an understanding of its neurobiological underpinnings is still in the early stages. Previous research suggests that BED may be an overeating syndrome characterized by a hyper-responsiveness to reward, and a strong dopamine signaling in the neuro-circuitry that regulates pleasure and appetitive behaviors. We investigated...
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