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Article

Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats.

Physiology & behavior - 1 Dec 2015

Sinclair Elaine B, Culbert Kristen M, Gradl Dana R, Richardson Kimberlei A, Klump Kelly L, Sisk Cheryl L

Abstract excerpt

Binge eating is a key symptom of many eating disorders (e.g. binge eating disorder, bulimia nervosa, anorexia nervosa binge/purge type), yet the neurobiological underpinnings of binge eating are poorly understood. The mesocorticolimbic reward circuit, including the nucleus accumbens and the medial prefrontal cortex, is likely involved because this circuit mediates the hedonic value and incentive salience of...

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Identifiers

PMID: 26459117
DOI: 10.1016/j.physbeh.2015.10.012
PMCID: PMC5645798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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