Contrasting mutation patterns in haploid and diploid cells from two yeast species.

Abstract excerpt

There is significant variation in the rate and spectrum of spontaneous mutations among taxa. How this variation is shaped by natural selection remains a subject of debate. The drift-barrier hypothesis proposes that selection generally favors lower mutation rates due to the risk of deleterious mutations but acts less effectively against weak mutator alleles in smaller populations, allowing the mutation rate to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diploidy
• Share to Haploidy
• Share to Mutation