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Article

Integration of genetic risk, cardiometabolic diseases, and cognitive impairment among African American adults.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Feb 2026

Dagli Chaitali, Armstrong Nicole D, Kim Daeeun, Raffield Laura M, Tiwari Hemant K, Cushman Mary, Judd Suzanne E, Crowe Michael, Howard Virginia J, Irvin Marguerite R

Abstract excerpt

BACKGROUND: African American (AA) adults have a high burden of late-life cognitive impairment (CI) and dementia but remain underrepresented in genetic epidemiology studies. Genetic risk and cardiometabolic diseases (CMDs) contribute to dementia risk. This study investigated whether genetic susceptibility and CMDs were associated with a composite CI outcome and whether CMDs modified these associations. METHODS: In...

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Identifiers

PMID: 41435906
DOI: 10.1016/j.jstrokecerebrovasdis.2025.108535
PMCID: PMC13033335

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APOE
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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