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Article

The role of genomic-informed risk assessments in predicting dementia outcomes.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Nov 2025

Andrews Shea J, Tolosa-Tort Paulina, Jonson Caroline, Fulton-Howard Brian, Renton Alan E, Yokoyama Jennifer S, Yaffe Kristine

Abstract excerpt

INTRODUCTION: By integrating genetic and clinical risk factors into genomic-informed dementia risk reports, healthcare providers can offer patients detailed risk profiles to facilitate understanding of individual risk and support the implementation of personalized strategies for promoting brain health. METHODS: We constructed an additive score comprising the modified Cardiovascular Risk Factors, Aging, and...

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Aged, 80 and over
Alzheimer Disease
Apolipoproteins E
Dementia
Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Assessment

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Open in PubMed Open full text

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PMID: 41268856
DOI: 10.1002/alz.70826
PMCID: PMC12635868

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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