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Article

Galectin-1 promotes an M2 macrophage response to polydioxanone scaffolds.

Journal of biomedical materials research. Part A - 1 Sept 2017

Abebayehu Daniel, Spence Andrew, Boyan Barbara D, Schwartz Zvi, Ryan John J, McClure Michael J

Abstract excerpt

Regulating soft tissue repair to prevent fibrosis and promote regeneration is central to creating a microenvironment conducive to soft tissue development. Macrophages play an important role in this process. The macrophage response can be modulated using biomaterials, altering cytokine and growth factor secretion to promote regeneration. Electrospun polydioxanone (PDO) fiber scaffolds promoted an M2 phenotype when...

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Arginase
Cytokines
Extracellular Signal-Regulated MAP Kinases
Inflammation Mediators
Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nitric Oxide Synthase Type II

Tissue Scaffolds

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Identifiers

PMID: 28544348
DOI: 10.1002/jbm.a.36113
PMCID: PMC5563977

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