Article
Large DNA and protein language models enhance discovery of deleterious mutations in maize.
Genome biology - 5 Dec 2025
Wang Yiru, He Cheng, Wang Qiqi, Li Rui, Qin Yang, Wang Hongwu, Gou Mingyue, Zhang Xuebin, Li Huiyong, Huang Quansheng, Liu Xinfang, Yang Jinliang, White Frank F, Fu Junjie, Liu Sanzhen, Zheng Jun
Abstract excerpt
BACKGROUND: The maize inbred line Chang7-2 and derived lines are important male donors for hybrid production, contributing significantly to the development of high-yield and stress-tolerant hybrids. Additionally, Chang7-2 serves as a valuable model inbred line for genetic and genomic studies, facilitating the discovery of genes underlying hybrid vigor and other agronomic traits. RESULTS: Here, a reference genome...
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