Article
Unraveling Prevalence and Effects of Deleterious Mutations in Maize Elite Lines across Decades of Modern Breeding.
Molecular biology and evolution - 3 Aug 2023
Sun Shichao, Wang Baobao, Li Changyu, Xu Gen, Yang Jinliang, Hufford Matthew B, Ross-Ibarra Jeffrey, Wang Haiyang, Wang Li
Abstract excerpt
Future breeding is likely to involve the detection and removal of deleterious alleles, which are mutations that negatively affect crop fitness. However, little is known about the prevalence of such mutations and their effects on phenotypic traits in the context of modern crop breeding. To address this, we examined the number and frequency of deleterious mutations in 350 elite maize inbred lines developed over the...
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