Shared Genotypic Architectures of Stage III/IV Grade C Periodontitis Under 35 Years of Age (Former Aggressive Periodontitis) and Abnormal Root Morphology: A Family-Based Study.

Abstract excerpt

AIM: To identify shared genetic architectures and molecular pathways underlying the frequent co-occurrence of stage III/IV grade C periodontitis under 35 years of age (PIII/IV-C< 35y) and abnormal root morphology (ARM), using a family-based SNP set and transcriptomic approach. MATERIALS AND METHODS: We conducted a family-based study using whole-genome genotyping of 148 Han Chinese individuals from 52 families,...

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