Article
Genome-wide association study of stage III/IV grade C periodontitis (former aggressive periodontitis) in a Spanish population.
Journal of clinical periodontology - 1 Jul 2021
de Coo Alicia, Cruz Raquel, Quintela Inés, Herrera David, Sanz Mariano, Diz Pedro, Rodríguez Grandío Segundo, Vallcorba Nuria, Ramos Isabel, Oteo Alfonso, Serrano Cristina, Esmatges Alejandro, Enrile Francisco, Mateos Leopoldo, García Roberto, Álvarez-Novoa Pablo, Noguerol Blas, Zabalegui Ion, Blanco-Moreno José, Alonso Ángel, Lorenzo Ramón, Carracedo Angel, Blanco Juan
Abstract excerpt
AIM: To identify loci associated with stages III/IV, grade C periodontitis (PIII/IV-C) through a genome-wide association study (GWAS). MATERIALS AND METHODS: 441 Caucasian Spanish PIII/IV-C cases from the SEPA Network of Research Clinics and 1141 controls from the Banco Nacional de ADN were genotyped with "Axiom Spain Biobank Array," which contains 757836 markers, including rare and low-frequency Spanish...
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