A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci.

doi:10.1111/jcpe.13922

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Article

A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci.

Journal of clinical periodontology - 1 Apr 2024

De Almeida Silvia Diz, Richter Gesa M, de Coo Alicia, Jepsen Søren, Kapferer-Seebacher Ines, Dommisch Henrik, Berger Klaus, Laudes Matthias, Lieb Wolfgang, Loos Bruno G, van der Velde Nathalie, van Schoor Natasja, de Groot Lisette, Blanco Juan, Carracedo Angel, Cruz Raquel, Schaefer Arne S

Abstract excerpt

AIM: Few genome-wide association studies (GWAS) have been conducted for severe forms of periodontitis (stage III/IV grade C), and the number of known risk genes is scarce. To identify further genetic risk variants to improve the understanding of the disease aetiology, a GWAS meta-analysis in cases with a diagnosis at ≤35 years of age was performed. MATERIALS AND METHODS: Genotypes from German, Dutch and Spanish...

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PMID: 38140892
DOI: 10.1111/jcpe.13922

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