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Article

Photon-Counting Micro-CT for Bone Morphometry in Murine Models.

Tomography (Ann Arbor, Mich.) - 13 Nov 2025

Nadkarni Rohan, Han Zay Yar, Allphin Alex J, Clark Darin P, Badea Alexandra, Badea Cristian T

Abstract excerpt

BACKGROUND/OBJECTIVES: This study evaluates photon-counting CT (PCCT) for the imaging of mouse femurs and investigates how APOE genotype, sex, and humanized nitric oxide synthase (HN) expression influence bone morphology during aging. METHODS: A custom-built micro-CT system with a photon-counting detector (PCD) was used to acquire dual-energy scans of mouse femur samples. PCCT projections were corrected for tile...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41295560
DOI: 10.3390/tomography11110127
PMCID: PMC12655917

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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