Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional causal association and shared anti-inflammatory target of asthma and atopic dermatitis: a Mendelian randomization and colocalisation study.

BMC pulmonary medicine - 25 Nov 2025

Bi Jirui, Bi Jihong, Ni Xing, Lu Lin, Yin Tingting, Mao Shaohua, Zhang Run, He Juan

Abstract excerpt

BACKGROUND: To investigate the causal relationship between asthma and atopic dermatitis (AD), and to identify potential therapeutic targets for their co-treatment. METHODS: All summary statistics were sourced from publicly available genome‑wide association studies. Two‑sample Mendelian randomization (MR) analysis was employed to assess the causal relationship between asthma and AD, as well as the causal effects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Interleukin-6

Share to Mendelian Randomization Analysis

Share to Molecular Docking Simulation

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 41291613
DOI: 10.1186/s12890-025-04042-9
PMCID: PMC12763921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional causal association and shared anti-inflammatory target of asthma and atopic dermatitis: a Mendelian randomization and colocalisation study.PMID 41291613Read ↗

Exploring causal correlations between circulating cytokines and atopic dermatitis: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Exploring the therapeutic potential of interleukin-6 receptor blockade in autoimmune diseases using drug target mendelian randomization.Semantic proximity Read ↗

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic diseaseSemantic proximity Read ↗

Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease.Semantic proximity Read ↗

Exploring the causal relationship between inflammatory cytokines and C-reactive protein levels and atopic dermatitis: a two-way two-sample Mendelian randomization studySemantic proximity Read ↗

Potential drug targets for asthma identified through Mendelian randomization analysisSemantic proximity Read ↗

Association of atopic dermatitis with autoimmune diseases: A bidirectional and multivariable two-sample mendelian randomization studySemantic proximity Read ↗

Genetic Correlations and Causal Relationships Among Allergic Diseases: A Comprehensive Mendelian Randomization Study With Multiomic Mediation Analysis.Semantic proximity Read ↗

Asthma and atopic dermatitis as risk factors for rheumatoid arthritis: a bidirectional mendelian randomization study.Semantic proximity Read ↗

Atopic disease and inflammatory bowel disease: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

Causal relationships between allergic and autoimmune diseases with chronic rhinosinusitis.Semantic proximity Read ↗

Interleukin-33 links asthma to alopecia areata: Mendelian randomization and mediation analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.