Article
Asthma and atopic dermatitis as risk factors for rheumatoid arthritis: a bidirectional mendelian randomization study.
BMC medical genomics - 3 Mar 2023
Chen Chuiji, Su Le, Duan Wenhao, Zheng Yansen, Zhang Dianzhong, Wang Yucai
Abstract excerpt
BACKGROUND: Previous observational studies have shown an association between asthma, atopic dermatitis (AD) and rheumatoid arthritis (RA). However, the bidirectional cause-effect chain between asthma and AD and RA has not been proven yet. METHODS: We performed bidirectional two-sample Mendelian randomization (TSMR) and selected single nucleotide polymorphisms (SNPs) associated with asthma, AD, and RA as...
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