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Article

Genetic Correlations and Causal Relationships Among Allergic Diseases: A Comprehensive Mendelian Randomization Study With Multiomic Mediation Analysis.

Mediators of inflammation - 1 Jan 2026

Zhang Ping-An, Wang Jie-Lin, Fu Shi-Yan, Luo Hua-Lian, Li Nai-Jian, Qin Run-Dong, Li Jing

Abstract excerpt

BACKGROUND: Allergic diseases, including allergic asthma (AA), allergic rhinitis (AR), atopic dermatitis (AD), and allergic conjunctivitis (AC), often coexist. However, the specific inflammatory mediators driving their shared mechanisms remain unclear. This study explored causal relationships and identified multiomic mediators among allergic diseases using Mendelian randomization (MR). METHODS: Large-scale GWAS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41954291
DOI: 10.1155/mi/5466012
PMCID: PMC13063389

Genes

AR
ABHD12
SEZ6L2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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