Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutagenic analysis of the Clostridium difficile flagellar proteins, FliC and FliD, and their contribution to virulence in hamsters.

Infection and immunity - 1 Oct 2011

Dingle Tanis C, Mulvey George L, Armstrong Glen D

Abstract excerpt

Although toxins A and B are known to be important contributors to the acute phase of Clostridium difficile infection, the role of colonization and adherence to host tissues in the overall pathogenesis of these organisms remains unclear. Consequently, we used the recently introduced intron-based ClosTron gene interruption system to eliminate the expression of two reported C. difficile colonization factors, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Adhesion
Share to Caco-2 Cells
Share to Clostridioides difficile

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clostridium Infections

Share to Cricetinae

Share to Epithelial Cells

Share to Flagella

Share to Intestines

Source

Open in PubMed Open full text

Identifiers

PMID: 21788384
DOI: 10.1128/IAI.05305-11
PMCID: PMC3187235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutagenic analysis of the Clostridium difficile flagellar proteins, FliC and FliD, and their contribution to virulence in hamsters.PMID 21788384Read ↗

Dissecting the role of flagellar subunits in C. difficile mucosal colonization.Semantic proximity Read ↗

Dissecting the Role of Flagellar Subunits in <i>C. difficile</i> Mucosal ColonizationSemantic proximity Read ↗

Control of Clostridioides difficile virulence and physiology by the flagellin homeostasis checkpoint FliC-FliW-CsrA in the absence of motility.Semantic proximity Read ↗

The Role of Flagella in Clostridium difficile Pathogenesis: Comparison between a Non-Epidemic and an Epidemic StrainSemantic proximity Read ↗

Control of <i>Clostridiodes difficile</i> virulence and physiology by the flagellin homeostasis checkpoint FliC-FliW-CsrA in the absence of motilitySemantic proximity Read ↗

Modulation of toxin production by the flagellar regulon in Clostridium difficile.Semantic proximity Read ↗

The Flagellin FliC of Clostridium difficile Is Responsible for Pleiotropic Gene Regulation during In Vivo InfectionSemantic proximity Read ↗

The role of flagella in Clostridium difficile pathogenicity.Semantic proximity Read ↗

Inactivation of the flagellin gene of Salmonella enterica serotype enteritidis strongly reduces invasion into differentiated Caco-2 cells.Semantic proximity Read ↗

Molecular Cloning and Characterization of the <i>Helicobacter pylori fliD</i> Gene, an Essential Factor in Flagellar Structure and MotilitySemantic proximity Read ↗

Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infectionSemantic proximity Read ↗

Flagellar Cap Protein FliD Mediates Adherence of Atypical Enteropathogenic Escherichia coli to Enterocyte Microvilli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.