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Article

Clinical, Molecular, and Bioinformatic Study of Common Thrombophilia Mutation Factor V Leiden.

Advances in experimental medicine and biology - 1 Jan 2026

Angelopoulou Antonia, Papakonstantinou Eleni, Vlachakis Dimitrios, Chrousos George P, Cosmidis Nikolaos, Yapijakis Christos

Abstract excerpt

BACKGROUND: The most common genetic cause associated with thrombophilia is Leiden mutation (G1691A) of the coagulation factor V (F5) gene. MATERIALS AND METHODS: Data collected anonymously from 355 unrelated Greeks examined for the above mutation were analyzed. Bioinformatic investigation was conducted for factor V, including phylogenetic analysis, genetic network analysis, and 3D modeling of wild-type and Leiden...

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Identifiers

PMID: 41273552
DOI: 10.1007/978-3-032-03398-7_10

Genes

F5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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