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Article

Peripheral mononuclear cells and systemic lupus erythematosus association: Integrated study of single-cell sequencing and mendelian randomization analysis.

Lupus - 1 Dec 2024

Jian Shi, Li Han

Abstract excerpt

OBJECTIVE: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease predominantly affecting women. Despite advances in treatment, recent developments in single-cell RNA sequencing (scRNA-seq) and Mendelian randomization (MR) continue to facilitate the need for precision medicine. METHODS: Data obtained from the GSE135779 dataset underwent quality control, normalization, and dimensionality reduction...

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Share to Intracellular Signaling Peptides and Proteins
Share to Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39404110
DOI: 10.1177/09612033241292705

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